Check out the companies making the biggest moves midday: Alkermes — The biotech company dropped 9% as traders weighed phase 2 trial results for its ALKS 2680 drug, which aims to treat narcolepsy. While the company will be advancing the drug to a Phase 3 trial, a higher range of doses or a split dosing regimen may be required to achieve effectiveness in some patients. Bank stocks — The group rose broadly as Treasury yields declined, lifting the Dow Jones Industrial Average to all-time highs. Goldman Sachs and JPMorgan Chase rose 3.8% and 1%, respectively. The Financial Select Sector SPDR Fund (XLF) climbed 1%. RXO — Shares popped 6%, adding to Tuesday’s 5.7%. The stock jumped in the previous session following a Morgan Stanley upgrade to overweight from equal weight. Wednesday’s move put the freight carrier on pace for its best day in more than a month. GlobalFoundries — Shares fell over 3% despite higher-than-expected earnings in the third quarter. The semiconductor manufacturer posted earnings of 41 cents per share, excluding certain items, on revenue of $1.69 billion. Analysts polled by FactSet anticipated a profit of 38 cents per share on revenue of $1.68 billion. Nextracker — The solar power technology platform rebranded itself to Nextpower and said it anticipates $4.8 billion to $5.6 billion in revenue by 2030. The company also reaffirmed its full-year outlook for 2026. Shares fell nearly 9%. Advanced Micro Devices — The chipmaker jumped 9% in reaction to robust long-term growth targets made at its Financial Analyst Day , including an internal forecast that the company’s data center revenue will jump 60% annually in the next three to five years . BILL Holdings — Bloomberg reported early Wednesday that the financial operations firm is considering a potential sale to a larger industry rival or private equity firm, pushing up BILL shares nearly 12%. Clearwater Analytics — The stock rose 9% after Bloomberg reported early Wednesday that the cloud-native platforms firm is weighing the possibility of selling its business. On Holding — The Swiss athletic shoemaker surged 19% after raising its forward guidance for a third straight quarter and beating revenue and earnings estimates. On also said it wouldn’t need to lean on Black Friday promotions to boost demand. BigBear.AI — The AI defense stock popped 13%, extending its gains from Tuesday when shares advanced more than 6%. On Monday, BigBear.AI’s announced its latest earnings , including a definitive agreement to acquire Ask Sage, a generative AI platform. Alcon — U.S.-listed shares added 4% after the Swiss eye care company’s third-quarter adjusted earnings of 79 cents per share topped the 76 cents expected by analysts polled by FactSet. Quarterly revenue came in below the consensus estimate, but Alcon reaffirmed its top and bottom-line guidance. Sony — The gaming and software company gained 3.6% after saying its tariff burden will likely equal about $324 million in operating profit for the year ending March, or nearly 30% less than previously expected. Oklo — The nuclear technology company 5.5% after extending its collaboration with the Idaho National Laboratory. Circle Internet — Shares fell 11% even after the stablecoin issuer posted earnings and revenue that beat expectations. Circle also reported that it accounts for 29% of the stablecoin market. Circle shares are down 40% in the past three months. — CNBC’s Sarah Min, Alex Harring and Michelle Fox, Liz Napolitano, Itzel Franco and Christina Cheddar-Berk contributed reporting.
